Longevity

Glutathione

Glutathione is a tripeptide that the body makes and uses as one of its main antioxidants. It is offered as a compounded injectable and as an oral melt. Here is what it is, what the research does and does not show, and how it works through a licensed physician.

Compounded. Not FDA-approved. Available by prescription only.
Tripeptide Antioxidant Compounded Prescription only

Included with every protocol

  • Coaching and the Avida app — included, at no extra cost
  • Physician review before it ships, and monitoring while you are on protocol
  • Delivered to your door by a licensed US pharmacy, refills managed for you
XCeed Glutathione vial Physician-reviewed before it ships

What it is

What glutathione is

Glutathione is a tripeptide, a molecule made of three amino acids (glutamate, cysteine, and glycine), that the body produces naturally. It is one of the body's most important antioxidants and takes part in many normal cellular processes. Glutathione offered through XCeed is compounded, and is offered as an injectable and as an oral melt. Beyond that established biology, we make no claims about what supplemental glutathione will do for you. Whether it fits your goals is a decision for a licensed physician.

The evidence

What the research says, and what it does not

Glutathione's role as an antioxidant in the body is well established. What is much less settled is whether taking supplemental glutathione, particularly by injection, produces a meaningful health benefit in people. The human evidence is limited and mixed. We present the research so you can be informed and ask your physician good questions. We make no claims about what glutathione will do for you.

Human
Richie, Nichenametla, Neidig et al. (2015) — European Journal of Nutrition 54(2):251–63

Oral glutathione, not injectable. A six-month randomised, double-blind, placebo-controlled trial in 54 healthy non-smoking adults, measuring whether oral glutathione raises glutathione levels in blood and tissue. Levels rose in a dose-dependent way and returned to baseline after a one-month washout. It measured levels, not health outcomes.

Human
Allen & Bradley (2011) — Journal of Alternative and Complementary Medicine 17(9):827–33

Oral glutathione, and a null result. A four-week randomised trial in healthy adults that found no change in glutathione levels or in markers of oxidative stress. It disagrees with the trial above, and we show both.

How to read this list: both human trials we can point to used oral glutathione, and they disagree with each other. Both therefore speak more directly to the oral form than to the injection, and we have not identified a controlled human trial of injectable glutathione in healthy adults. We would rather say that plainly than present oral evidence as though it transfers to an injection.

Safety

Safety and what to discuss with your physician

A licensed physician reviews your history and decides whether glutathione is appropriate for you, and monitors you while you are on protocol. Reactions at the injection site can occur. Injectable glutathione should be used only under a physician's direction, and a physician can explain the considerations that apply to it. People who are pregnant or breastfeeding, and anyone with a significant medical condition, should review it with a physician first.

The process

How to get glutathione through XCeed

01

Tell us your goal

Complete a short medical intake.

02

A physician decides

If a protocol is right for you, they prescribe it. If it is not, they tell you.

03

Delivered, with a coach

A US-based pharmacy dispenses it, and the Avida app and a coach come with it.

See if it is right for you

No.Compounded · not FDA-approved

Is glutathione FDA-approved?

No. Glutathione offered through XCeed is compounded and is not FDA-approved. It is prescribed by a licensed physician and dispensed by a licensed US-based pharmacy.

Questions

Frequently asked questions

Is glutathione FDA-approved?

No. What you would receive is compounded and is not FDA-approved.

What is glutathione?

A tripeptide the body makes naturally and uses as one of its main antioxidants.

Does supplemental glutathione work?

Its role in the body is well understood, but whether supplemental glutathione by injection produces a health benefit in people is not well established, and the evidence is mixed. We do not promise a result.

Do I need a prescription?

Yes. A licensed physician reviews your intake and decides before anything is dispensed.

How is it taken?

As an injection, or as an oral melt that dissolves in the mouth. Both are taken under a physician's direction, and your physician sets the specifics and can help you choose between them.

Start here

Want to talk to a physician about glutathione?

Start with a short intake. A licensed physician decides what, if anything, is right for you.